Ensembl 107 and Ensembl Genomes 54 have now been released. Check out our site for exciting new updates to regulatory annotations, updated vertebrate genomes and lots of new metazoan species.
Continue readingTag: VEP
What’s coming in Ensembl release 107 / Ensembl Genomes 54?
Ensembl 107 and Ensembl Genomes 54 are expected in June 2022. Check out what we’re up to, although we can’t guarantee everything listed here will make it into the final release.
Continue readingCool stuff Ensembl VEP can do: run faster with Nextflow
Ensembl VEP is now wrapped in a Nextflow pipeline which means you can analyse large variant sets more quickly using simple parallelisation.
Continue readingFree Ensembl Browser and REST API virtual workshops in March
Sign up for our recurring virtual series covering the genome browser and the REST API. Both workshops will be held between Tuesday – Thursday, with the Browser on 8th-10th March and the REST API on 15th-17th March 2022 (2pm-5pm GMT). Read on for more information and registration instructions.
Continue readingCool stuff Ensembl VEP can do: flagging variants predicted to allow NMD escape
A new plugin was released in Ensembl VEP version 105 which reports when a variant introducing a premature stop codon may allow the transcript to escape nonsense-mediated decay (NMD).
Continue readingUpdated G2P terms supported in Ensembl VEP
Recent changes to the terms used in the G2P database are aligned with global standards, but are not compatible with old versions of the VEP G2P plugin. We’ve updated the latest version of the VEP G2P plugin (Ensembl 105) to be compatible with both the old and new formats.
Continue readingEnsembl 105 has been released
Hooray! Ensembl 105 and Ensembl Genomes 52 have now been released. We have got updates to the human frequency data and new and updated genomes for vertebrates, fungi and plant species. We are also very excited to integrate AlphaFold data for Arabidopsis thaliana in Ensembl Plants.
Continue readingCool stuff Ensembl VEP can do: protein annotations from neXtProt
Together with the neXtProt team, we’ve created a plugin for the command-line VEP tool to retrieve and report information about the protein location of missense and stop gained variants.
Continue readingUsing Ensembl VEP with Windows 10
Ensembl VEP has been developed for use on Linux systems and we recommend installing on a Linux system for the optimal installation and usage experience. However, we occasionally receive queries about using VEP in the Windows environment – this guide will help you get going if you are using Windows 10.
Continue readingUpdate: Temporary disruption to Ensembl Tools and Archive services is now resolved
Disruptions are now resolved and Ensembl services are back to normal.
We have temporarily disabled Ensembl Tools, for example VEP and BLAST/BLAT on our vertebrate live websites (www, US East, US West, Asia and GRCh37) whilst we investigate a problem with the underlying infrastructure in our Harlow data center. Some of our archive resources are also currently unavailable. We are sorry for the trouble this may cause and we hope to restore them as soon as we can. Other resources such as our FTP site and public MySQL servers are unaffected.