Together with the neXtProt team, we’ve created a plugin for the command-line VEP tool to retrieve and report information about the protein location of missense and stop gained variants.
Continue readingWhat’s coming in Ensembl release 105 / Ensembl Genomes 52?
Ensembl 105 and Ensembl Genomes 52 are expected in October 2021. Check out what we’re up to, although we can’t guarantee everything listed here will make it into the final release.
Continue readingFree Ensembl Browser and REST API virtual workshops in September
Update: Registration is now closed, as all of the available places on the virtual Ensembl browser and REST API workshops have been filled. If you would like to be added to the waiting list, please e-mail the Ensembl Helpdesk.
We’ve got another round of our recurring virtual series covering the genome browser and the REST API. Both workshops will be held between Tuesday – Thursday, with the Browser on 7th-9th September and the REST API on 14th-16th September 2021 (2pm-5pm BST). Read on for more information and registration instructions.
Continue readingUsing Ensembl VEP with Windows 10
Ensembl VEP has been developed for use on Linux systems and we recommend installing on a Linux system for the optimal installation and usage experience. However, we occasionally receive queries about using VEP in the Windows environment – this guide will help you get going if you are using Windows 10.
Continue readingUpdate: Temporary disruption to Ensembl Tools and Archive services is now resolved
Disruptions are now resolved and Ensembl services are back to normal.
We have temporarily disabled Ensembl Tools, for example VEP and BLAST/BLAT on our vertebrate live websites (www, US East, US West, Asia and GRCh37) whilst we investigate a problem with the underlying infrastructure in our Harlow data center. Some of our archive resources are also currently unavailable. We are sorry for the trouble this may cause and we hope to restore them as soon as we can. Other resources such as our FTP site and public MySQL servers are unaffected.
Ensembl’s efforts towards a greener future
Ensembl is rapidly working towards annotating large collections of genomes based on the nodes of the Earth BioGenome Project. Our aim is to characterise the genome of new species to reinvigorate our understanding of biological diversity, strengthen conservation efforts, and benefit human welfare. Read more to find out how Ensembl will contribute to tackle the climate change challenges that face the world today.
Continue readingCool stuff the VEP can do: Singularity
The quickest and most flexible way to run Ensembl VEP on large scale variant sets is to install and run it locally. Depending on the use case, the underlying architecture, and the available permissions, installing VEP prerequisites is prone to complications. To aid with this, we have made the VEP available with containers.
Continue readingFree Ensembl Browser and REST API virtual workshops in June
Have you missed out on the open Ensembl workshops in May? We’ve got another round of our recurring virtual series covering the genome browser and the REST API. Both workshops will be held between Tuesday – Thursday, with the Browser on 8th-10th June and the REST API on 15th-17th June 2021 (9am-12pm BST). Read on for more information and registration instructions.
Continue readingEnsembl 104 has been released
Ensembl 104 and Ensembl Genomes 51 are out! This release features updates to human and mouse genes, GRCh37 variation and regulation, new assemblies and variation for vertebrates, new plant species and a large update of the available metazoa data. We also said bye-bye to clone-based gene names and welcomed the new Ensembl Canonical transcripts.
Continue readingCool stuff Ensembl VEP can do: disease information from DisGeNET
To better understand how your variants might be linked to disease, you can add information from DisGeNET to your VEP analysis. DisGeNET integrates data from expert curated repositories, GWAS catalogues, animal models and the scientific literature, to provide disease associations with genes and variants.
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