The Ensembl VEP command-line tool can annotate and filter variants called against the latest human assemblies, including the telomere-to-telomere assembly of the CHM13 cell line (T2T-CHM13). In this blog post, we provide examples of how to run Ensembl VEP with these new assemblies and list the additional annotations supported via plugins.
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Integration of AlphaMissense scores into Ensembl
We’re excited to announce the integration of AlphaMissense pathogenicity scores into Ensembl! The display of AlphaMissense data in Ensembl and other EMBL-EBI resources aims to empower scientists to gain new insights, expand the exploration of genetic variation and the tolerance to change of different regions in proteins.
Continue readingEnsembl 112 has been released.
We are pleased to announce the release of Ensembl 112, and the corresponding release of Ensembl Genomes 59. We have some exciting new fish species, many more drosophila species and some incredible VEP updates.
Continue readingFree Ensembl Browser and REST API virtual workshops in May
Sign up for our virtual series covering the Ensembl genome browser and accessing Ensembl data via its REST API. Both workshops will be held from Tuesday to Thursday, with the browser course running from 7th to 9th May and REST API from 14th to 16th May 2024 (14:00-17:00 BST). Read on for more information and how to register.
Continue readingWhat’s coming in Ensembl release 112 / Ensembl Genomes 59?
Ensembl 112 and Ensembl Genomes 59 are expected in April 2024. Check out what we’re up to, although we can’t guarantee everything listed here will make it into the final release.
Continue readingCool stuff the Ensembl VEP can do: new options for custom annotation
During the latest Ensembl VEP releases, we have been enhancing the options available to you when you annotate variants against your own reference data as ‘custom annotation’. Here we detail some of those improvements.
Continue readingEnsembl 111 has been released!
We are pleased to announce the release of Ensembl 111, and the corresponding release of Ensembl Genomes 58 featuring a range of new Ensembl VEP plugins and tonnes of new and updated agricultural, fish, plant and metazoa species!
Genome assemblies and annotation for many new species are also being continuously added to the Ensembl Rapid Release genome browser.
Continue readingDowntime of Ensembl tools
Due to scheduled maintenance work, Ensembl tools will be temporarily unavailable on Tuesday 6th February 2024 between 11:30 and 13:00 (GMT).
Continue readingCool stuff the Ensembl VEP can do: easy installation and annotation using Docker and Singularity
Here we will highlight how to get the most out of containers, enabling you to quickly start running any version of Ensembl VEP on a computer with Docker/Singularity installed. We have improved the Ensembl VEP Docker build process and updated our instructions on how to use Docker and Singularity.
Continue readingWhat’s coming in Ensembl 111 / Ensembl Genomes 58
Ensembl 111 and Ensembl Genomes 58 are expected to be released in December 2023. Find out what’s coming in the new release, although we cannot guarantee everything listed here will make it into the final release.
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