What’s coming in Ensembl release 106 / Ensembl Genomes 53?

Ensembl 106 and Ensembl Genomes 53 are expected in February 2022. Check out what we’re up to, although we can’t guarantee everything listed here will make it into the final release.


  • New AlphaFoldDB data for human
  • Human frequency data updated to gnomAD 3.1


New assemblies and annotation:

  • Atlantic salmon (Salmo salar) assembly and gene set updated from ICSASG_v2 to Ssal_v3.1
  • Rainbow trout (Oncorhynchus mykiss) assembly and gene set updated from Omyk_1.0 to USDA_OmykA_1.1
  • European seabass (Dicentrarchus labrax) assembly and gene set updated from seabass_V1.0 to dlabrax2021
  • An additional Carp (Cyprinus carpio carpio) assembly (Cypcar_WagV4.0) and gene set update has been added

These genomes are all part of the AquaFAANG project.


New species:


  • Rhipicephalus microplus (southern cattle tick)
  • Rhipicephalus sanguineus (brown dog tick)
  • Haemaphysalis longicornis (longhorned tick)
  • Ixodes persulcatus (taiga tick)
  • Dermacentor silvarum
  • Hyalomma asiaticum

Parasitic worms:

  • Ascaris suum
  • Hymenolepis microstoma
  • Trichuris muris
  • Necator americanus

New assemblies and annotation:

  • Culex quinquefasciatus (Southern house mosquito)
  • Acyrthosiphon pisum (pea aphid)
  • Anoplophora glabripennis (Asian long-horned beetle)
  • Bombus impatiens (Common eastern bumblebee)
  • Bombyx mori (Domestic silkworm)
  • Danaus plexippus (Monarch butterfly)
  • Glossina fuscipes (Tsetse fly)
  • Sarcoptes scabiei (Itch mite)
  • Solenopsis invicta (Red fire ant)
  • Teleopsis dalmanni (Malaysian stalk-eyed fly)
  • Schistosoma mansoni
  • Ixodes scapularis

Annotation update:

  • Brugia malayi
  • Caenorhabditis brenneri
  • Caenorhabditis briggsae
  • Caenorhabditis elegans
  • Caenorhabditis japonica
  • Caenorhabditis remanei
  • Onchocerca volvulus
  • Pristionchus pacificus
  • Strongyloides ratti


New species:

  • Secale cereale (Rye)
  • Corymbia citriodora 
  • Pisum sativum (Pea)

New assemblies and annotation:

  • Vitis vinifera (grape)
  • Triticum urartu    

Other Updates and Highlights

  • New AlphaFoldDB data for
    • Mus musculus (mouse)
    • Danio rerio (zebrafish)
    • Zea mays (maize)
    • Glycine max (soybean)
  • Retirement of Ensembl mobile site
  • Retirement of Ensembl 86 and Ensembl 87 archive sites
  • Update to VariantRecoder REST endpoints to return variant names in other databases (UniProt, ClinVar)  and MANE status
  • New UTR annotation plugin for web-based VEP
  • New IntAct plugin 
  • ATAC-Seq tracks from GENE-SWitCH added for pig
  • Wheat specific gene trees for different wheat cultivars and relatives
  • BioMart will only show human variant consequences for MANE transcripts