Ensembl is currently undergoing a major transformation to provide faster, more flexible, and more scalable access to genome data. As outlined in our Ensembl 2026 publication, work on the new platform is well underway and can already be explored at beta.ensembl.org. In this blog, we are sharing important information about upcoming changes to Ensembl data access, including timelines, new services, and what you need to do to prepare.

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Ensembl VEP makes it easy to annotate your variants with the reference data essential to variant filtering and interpretation. This includes the results of multiplex assays of variant effect (MAVEs) which report on observed cellular phenotypes across nearly all possible variants in specific targeted regulatory or coding regions.

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We are pleased to announce the release of Ensembl 113, and the corresponding release of Ensembl Genomes 60. This release brings major gene and regulatory feature annotation updates in Homo sapiens (Human) and Mus musculus (Mouse). We have updated existing genomes and added additional genomes across the different Ensembl sites, including livestock breeds in Ensembl, three new species in Ensembl Plants and 26 new species in Ensembl Metazoa. Can’t find the species you are looking for? Don’t forget that new and exciting genome assemblies and annotations are continuously added to Ensembl Rapid Release!

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Sign up for our virtual series covering the Ensembl genome browser and accessing Ensembl data via its REST API. Both workshops will be held from Tuesday to Thursday, with the browser course running from 7th to 9th May and REST API from 14th to 16th May 2024 (14:00-17:00 BST). Read on for more information and how to register.

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Sign up for our virtual series covering the Ensembl genome browser and accessing Ensembl data via its REST API. Both workshops will be held from Tuesday to Thursday, with the browser course running from 10th to 12th October and the REST API course from 17th to 19th July (09:00 – 12:00 BST). Read on for more information and how to register.

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Sign up for our virtual series covering the Ensembl genome browser and accessing Ensembl data via its REST API. Both workshops will be held from Tuesday to Thursday, with the browser course running from 11th to 13th July and the REST API course from 18th to 20th July (14:00 – 17:00 BST). Read on for more information and how to register.

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We have made a number of changes in Ensembl Compara Perl API and REST API endpoints. These changes allow Ensembl to handle non-unique member stable IDs when retrieving comparative genomics data via the APIs. These changes will come into effect in Ensembl release 110 and all old endpoints will be retired in release 112. Please continue reading if you regularly retrieve comparative genomics data via the Ensembl APIs.

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