In July, we talked to Reham Fatima, a member of the Havana team. The Havana team carry out manual annotation on human, mouse, zebrafish and rat genomes. Reham has contributed to the MANE and GENCODE projects. Read more about Reham’s work at EMBL-EBI and what kind of cuisine she likes the most. You can also see some amazing photographs she has taken in her free time.

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It’s probably reasonable to assume that the coding sequence (CDS) of a protein-coding transcript model is the feature that is of primary interest to most people who use Ensembl. However, both the 5’ and 3’ untranslated regions (UTRs) are important biological entities in their own right, and it is vital that we in Ensembl do the best we can to represent them accurately. However, the annotation of these UTRs is complicated, so we’re going to focus on exploring the annotation process for 3’ UTRs in this article (Figure 1).

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