Ensembl 104 and Ensembl Genomes 51 are out! This release features updates to human and mouse genes, GRCh37 variation and regulation, new assemblies and variation for vertebrates, new plant species and a large update of the available metazoa data. We also said bye-bye to clone-based gene names and welcomed the new Ensembl Canonical transcripts.

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Upcoming Ensembl release 104 will bring an update to the Ensembl Canonical transcripts. The new Ensembl Canonical definition will prioritise well-supported biologically representative, highly expressed and highly conserved transcripts. MANE Select will be used as the canonical transcript for human protein coding genes where available.

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Human, mouse, rat and zebrafish genes without an official gene symbol, have been conventionally named after BAC clones in Ensembl. We plan to remove these names in Ensembl release 104 and resort to using the Ensembl gene stable IDs instead, in line with practices adopted for all other vertebrate species. 

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