Ensembl VEP makes it easy to annotate your variants with the reference data essential to variant filtering and interpretation. This includes the results of multiplex assays of variant effect (MAVEs) which report on observed cellular phenotypes across nearly all possible variants in specific targeted regulatory or coding regions.
Continue readingTag: Bioinformatics
Getting to know us Jorge from Ensembl Outreach
Welcome to our Getting to know us (a.k.a. Teamsembl) blog series, where we talk to Ensembl colleagues and ask them a series of questions about their role in the project. For this month, we chatted with Jorge Batista da Rocha, who is the project leader of the Ensembl Outreach team. Join us as we learn more about Jorge’s role at Ensembl.
Continue readingEnsembl 115 has been released!
We are pleased to announce the release of Ensembl 115, and the corresponding release of Ensembl Genomes 62. In this release – around 121,000 new protein-coding transcripts have been added to the GRCh38 human reference gene set. Two new breeds of cattle are now available (UOA_Tuli_1 and UOA_Wagyu_1) and the sheep reference has been updated to ARS-UI_Ramb_v3.0. Seven new plant species have been added: four oats, two garden peas, and one lablab bean. We have also added two new export modes for Newick trees which help to avoid stable ID clashes.
Continue readingGetting to know us: Suzanna Dickson (visiting PhD student)
Welcome to our Teamsembl blog series, where we chat with folks from the Ensembl team to get a peek into what they do. This month, we got to know Suzanna Dickson, a visiting PhD student with the Ensembl Non-Vertebrates team. Check out what Suzanna has been up to during her placement and hear about her experiences working with us!
Continue readingGetting to know us: Jack Carpenter (visiting PhD student)
In our Getting to know us (a.k.a. Teamsembl) blog series, we talk to Ensembl colleagues and ask them a series of questions about their role in the project. In June, we talked to Jack Carpenter, who is a visiting PhD student within the Ensembl Non-Vertebrates team. Learn more about Jack’s placement at Ensembl and the experience he gained
Continue readingGetting to know us: Paulo from Ensembl Regulation
Welcome to our Getting to know us (a.k.a. Teamsembl) blog series, where we talk to Ensembl colleagues and ask them a series of questions about their role in the project. For this month, we chatted with Paulo Branco Lins, who is a bioinformatician and software developer within the Ensembl Regulation team. Join us as we learn more about Paulo’s role at Ensembl.
Continue readingEnsembl 114 has been released!
We are pleased to announce the release of Ensembl 114, and the corresponding release of Ensembl Genomes 61. This release brings an updated MANE set (v1.4) for the human GRCh38 assembly. We have updated existing data sets and added lots of exciting new genomes across the different Ensembl sites including rodents, livestock, plant, microbial and metazoa species. Variation data has been updated to EVA release 6 and is available for 39 species.
Continue readingGetting to know us: Natalie from Ensembl Automation
In our Getting to know us (a.k.a. Teamsembl) blog series we talk to Ensembl colleagues and ask them a series of questions. In February, we interviewed Natalie Willhoft, who recently took over the role of project leader of the Ensembl Automation team. Join us as we learn more about Natalie’s role, what she did before joining Ensembl and find out the exciting things she does with her family in her freetime.
Continue readingCool stuff Ensembl VEP can do: reduce the number of human transcripts you need to consider without missing results!
Ensembl VEP calculates the location and likely impact of variant alleles on genes, producing extensive annotations, but there are now a huge number of human transcripts to consider. The new GENCODE Primary transcript set streamlines the variant annotation process, saving time in both analysis and results filtering/ interpretation.
Continue readingGetting to know us: Jon from Ensembl Web
In our Getting to know us (a.k.a. Teamsembl) blog series we talk to Ensembl colleagues and ask them a series of questions. To kick off the year, we had the pleasure of interviewing Jon Keatley, who is the project leader of the Ensembl Web team. The Web team is the driving force behind developing, maintaining, and improving the Ensembl websites, including creating user interfaces and data visualisations. Join us as we explore Jon’s journey, the work he is currently involved in and the activities he enjoys with his family outside of work.
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