We are pleased to announce the release of Ensembl 110, and the corresponding release of Ensembl Genomes 57. This release brings exciting updates, such as the addition of regulation data to five animal genomes studied extensively in agriculture, the re-annotation of genomes in Ensembl Bacteria, and changes to REST API endpoints in our comparative genomics data. We have updated genomes across the different Ensembl sites, the addition of 15 rice varieties and invertebrate metazoan genome assemblies.

Can’t find a species you are looking for? Don’t forget that new genome assemblies and annotations are continuously added to Ensembl Rapid Release!

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We have made a number of changes in Ensembl Compara Perl API and REST API endpoints. These changes allow Ensembl to handle non-unique member stable IDs when retrieving comparative genomics data via the APIs. These changes will come into effect in Ensembl release 110 and all old endpoints will be retired in release 112. Please continue reading if you regularly retrieve comparative genomics data via the Ensembl APIs.

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We are pleased to announce the release of Ensembl 109, and the corresponding release of Ensembl Genomes 56. The release brings updates to donkey and horse assembly and lots of new Plants and Metazoa genomes. We have updated PolyPhen-2 and SIFT scores on VEP and Ensembl browser. And we have a shiny new resource that shows molecular interactions involving genes in Ensembl; ranging from pathogen-host interactions to symbiotic relationships across microbes and other Ensembl species.

New and exciting genome assemblies and annotations for many new species are being continuously added to the Ensembl Rapid Release genome browser.

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We are updating SIFT and PolyPhen-2 predictions of missense variant deleteriousness in the Ensembl browser and Ensembl VEP with the new release 109. We have recalculated all scores using newer software versions, updating PolyPhen-2 from 2.2.2 to 2.2.3 and SIFT from version 5.2.2 to 6.2.1. When we update software and reference data versions, we expect to see changes in some predictions. This is a guide as to what you can expect.

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