Computing Ensembl’s New Regulatory Annotation

We described in a previous post Ensembl’s new regulatory annotation of the genome. Now, we will go in greater detail into how we computed it. We started by running ChromHMM over 17 cell types, using publicly available ENCODE and Roadmap Continue reading Computing Ensembl’s New Regulatory Annotation

The New Ensembl Regulatory Annotation

GWAS after GWAS return statistically significant hits that are hard to interpret because they fall outside of coding regions, and this begs for more functional annotation of regulatory regions. We at Ensembl have been providing such an annotation for a Continue reading The New Ensembl Regulatory Annotation

Ensembl is the place!

May was a very busy month for Ensembl Outreach. Besides our customary user support activities, in 14 days, I crisscrossed the east coast of the US, attended the Biology of Genomes conference at CSHL and gave six Ensembl browser workshops at NIH-NHGRI, NIH-NIEHS and UNC-Chapel Continue reading Ensembl is the place!