What’s new in e84: Human: Incorporation of BLUEPRINT Epigenome data and methylation data Pairwise Linkage Disequilibrium (LD) calculation on LD variant page Track hub registry interface Transcript haplotype view Incorporation of BLUEPRINT Epigenome data BLUEPRINT is a large scale research Continue reading Ensembl 84 has been released!
Ensembl 84 is scheduled for March 2016 and includes: Updated gene sets and annotations Human: Incorporation of Blueprint epigenome data and methylation data Mouse: update to GENCODE M9 annotation Zebrafish: updated gene set, including manually annotated HAVANA annotation and RNAseq data update Continue reading What’s coming in Ensembl release 84
We described in a previous post Ensembl’s new regulatory annotation of the genome. Now, we will go in greater detail into how we computed it. We started by running ChromHMM over 17 cell types, using publicly available ENCODE and Roadmap Continue reading Computing Ensembl’s New Regulatory Annotation
GWAS after GWAS return statistically significant hits that are hard to interpret because they fall outside of coding regions, and this begs for more functional annotation of regulatory regions. We at Ensembl have been providing such an annotation for a Continue reading The New Ensembl Regulatory Annotation