Comparative Genomics Project Leader

Comparative Genomics Project Leader

Are you interested in joining the Ensembl project based in the UK, near Cambridge? The Comparative Genomics team currently has an open position for a Project leader. The Ensembl Compara team develops new and established methods for: whole genome sequence alignment, assignment of Continue reading Comparative Genomics Project Leader

New gene gain/loss tree view in Ensembl

Gene gain/loss tree view example

If you are interested in knowing the evolutionary history of your preferred Ensembl gene, you are in luck. Starting from this release (69) Ensembl has a new gene gain/loss tree view just for this purpose. This view shows the evolutionary Continue reading New gene gain/loss tree view in Ensembl

GERP constrained elements via DAS

It is now possible to get the GERP constrained elements via the DAS protocol. For instance the DAS command to get all the GERP elements on the BRCA2 gene (Human chr 13: 32889611-32973347) is:http://www.ensembl.org/das/Homo_sapiens.GRCh37.constrained_element/features?segment=13:32889611,32973347 By default, you obtain both the Continue reading GERP constrained elements via DAS

Which whole-genome multiple aligner? Pecan!

Comparing and assessing the quality of whole-genome multiple alignments is a difficult task. In the protein world, many mathematical models are available. They are based on synonymous and non-synonymous substitutions and the physicochemical similarities among the aminoacids. None of this Continue reading Which whole-genome multiple aligner? Pecan!