DNA methylation is an epigenetic mark known to be important in many biological processes, namely in the regulation of gene expression. In addition to MeDIP-Chip methylation datasets for 17 cell lines and tissues from Rakyan et al (2008), Ensembl now also Continue reading Human Methylation data in Ensembl
We are glad to announce the launch of our latest installment. Ensembl Release 63 (e63) includes a new high-coverage assembly for microbat (Myotis lucifugus), the most recent human and zebrafish manual gene annotations from Havana, and a fresh update of mouse Continue reading Ensembl 63 is out!
Ensembl provides annotations indicating regions in the genome that are experimentally verified to be bound by transcription factors (from ChIP-Seq experiments). Within these regions, we now also provide precise transcription factor binding sites. To generate these binding sites, we make use Continue reading Transcription Factor Binding Sites in Ensembl
Since release 58, the Ensembl Regulatory Build has been cell type specific. Regulatory Features are defined as sites of open chromatin which are potentially involved in gene regulation. These are built using data from different cell types, resulting in differing Continue reading Regulatory Build now Cell Type specific